购宝钱包APP

    购宝钱包APP /诊断试剂 /热门肿瘤标志物 /TMB /tTMB-P1(5.37) Reference Standard

    tTMB-P1(5.37) Reference Standard

    CBP80001-1

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    I. Background

    Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

     

    Sample ID

    Cat.No.

    Background

    Assay

    Comments

    DC198N0153

    CBP80001-1N

    B lymphoblast, Female

    500x WES

    Same individual

     

    DC198N0152

    CBP80001-1T

    Ductal breast carcinoma, Female

    500x WES

    IDT xGenExome Research Panel v1.0捕获,Target Region 39M, Probe Region 51M, CDS Region 33.52M;
    HiSeq X-TEN,af选择0.02 cut off,再过滤。
    DC198N0152 is 100% Tumor sample.

     

     

     

    Cut off =2%

    Cut off =3%

    Cut off =4%

    Cut off =5%

    Mutation Number

    180

    172

    168

    166

    TMB value

    5.37

    5.13

    5.01

    4.95 


    计算数据下载:DC198N0152.tmb


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